MPromDb (Mammalian Promoter Database) is a curated database to annotate gene promoters identified from ChIP-seq results. Users can search the database based on gene id/symbol, or by specific tissue/cell type and filter results based on any combination of tissue/cell specificity, Known/Novel, CpG/NonCpG, and protein-coding/non-coding gene promoters. Also integrated is a GBrowse genome browser with MPromDb for visualization of ChIP-seq profiles and to display the annotations.