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Links tagged with 'point mutation'

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CUPSATTool Content

http://cupsat.uni-koeln.de/

Protein > 3-D Structure Prediction
Protein > Biochemical Features

Cologne University Protein Stability Analysis Tool (CUPSAT) is a tool to analyse and predict protein stability changes upon point mutations (single amino acid mutations) for known protein structures.

NAR Web Server Issue 2006
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tagsmolecular structure point mutation protein databases protein denaturation protein engineering protein folding proteins secondary protein structure solvents

ESEfinderTool Content

http://rulai.cshl.edu/tools/ESE/

Expression > Splicing

ESEfinder is a web-based resource for identifing putative ESEs (exonic splicing enhancers), cis-acting motifs responsible for enhancing splicing.

NAR Web Server Issue 2003
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tagsbase sequence consensus sequence exons genetic enhancer elements humans messenger rna point mutation rna precursors rna sequence analysis rna splicing rna-binding proteins

GLUE, GLUE-IT, PEDEL, PEDEL-AA and DRIVeRTool Content

http://guinevere.otago.ac.nz/stats.html

DNA > Tools For the Bench

GLUE, PEDEL, and DRIVeR are tools for estimating completeness and diversity in randomized protein-encoding libraries; useful for guiding library design and for analyzing results. GLUE Including Translation (GLUE-IT) finds the expected amino acid completeness of libraries. PEDEL-AA calculates amino acid statistics for libraries generated by epPCR.

NAR Web Server Issue 2008
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tagsalgorithms chemical models codon computer simulation directed molecular evolution dna dna mutational analysis dna sequence analysis gene library genetic models genetic variation molecular evolution mutagenesis mutation peptide library point mutation polymerase chain reaction protein sequence analysis proteins statistical models

I-Mutant2.0Tool Content

http://gpcr2.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi

Protein > 3-D Structure Prediction
Protein > Molecular Dynamics and Docking

I-Mutant2.0 is a tool that can predict the effect of a single point mutation on protein stability from protein sequences or protein structures.

NAR Web Server Issue 2005
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tagsartificial intelligence point mutation protein engineering protein sequence analysis proteins tertiary protein structure thermodynamics

Rescue-ESETool Content

http://genes.mit.edu/burgelab/rescue-ese/

DNA > Structure and Sequence Feature Detection
Expression > Splicing

Server for the identification of hexnucleotide exonic splicing enhancers (ESEs). Also contains a list of 238 identified ESEs for human genes.

NAR Web Server Issue 2004
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tagsanimals complementary dna computational biology consensus sequence dna sequence analysis exons genes human genome humans hypoxanthine phosphoribosyltransferase introns messenger rna mice nucleic acid databases nucleic acid regulatory sequences oligonucleotides point mutation ribonucleic acid regulatory sequences rna precursors rna sequence analysis rna splicing tetraodontiformes zebrafish

RNAmutantsTool Content

http://bioinformatics.bc.edu/clotelab/RNAmutants/

RNA > Structure Prediction, Visualization, and Design

A web server to explore the effect of mutations on the RNA secondary structures.

NAR Web Server Issue 2009
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tagsnucleic acid conformation point mutation rna sequence analysis untranslated rna

RosettaBackrubTool Content

http://kortemmelab.ucsf.edu/backrub

Protein > 3-D Structure Prediction

The RosettaBackrub server computes near-native conformational ensembles from a single input protein structure in PDB format using the Backrub method.

NAR Web Server Issue 2010
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tagsmolecular models point mutation protein conformation protein interaction mapping protein sequence analysis proteins

SPACETool Content

http://ligin.weizmann.ac.il/space/

Protein > 3-D Structure Prediction

SPACE (Structure Prediction and Analysis based on Complementarity with Environment) is a suite of tools for predicting and analyzing structures of biomolecules and their complexes.

NAR Web Server Issue 2005
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tagsalgorithms amino acids automation bacterial proteins binding sites biotin computational biology factual databases formycins hydrogen bonding ligands molecular conformation molecular models molecular structure nucleic acids point mutation protein binding protein conformation protein databases proteins ribonucleotides ricin site-directed mutagenesis solvents streptavidin thermodynamics water x-ray crystallography