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Links tagged with 'histocompatibility antigens'

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EpiToolKitTool Content

http://www.epitoolkit.org

Human Genome > Health and Disease
Human Genome > Sequence Polymorphisms
Protein > Molecular Dynamics and Docking

A suite of tools for immunological research. EpiToolKit offers a variety of prediction methods that may be run simultaneously for predicting MHC Class I and II ligands, and minor histocompatibility antigens. The influence of sequence polymorphisms or mutations on potential T-cell epitopes may also be examined.

NAR Web Server Issue 2008
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tagsacetaminophen child computational biology dosage forms drug packaging france genetic polymorphism histocompatibility antigens humans ligands mutation neoplasm antigens non-narcotic analgesics oral administration peptides poison control centers poisoning protein sequence analysis t-lymphocyte epitopes

IEDB-3DDatabase Content

http://www.iedb.org

Protein > Databases

IEDB-3D is the 3D structural component of the Immune Epitope Database (IEDB). IEDB-3D catalogs B- and T-cell epitopes and Major Histocompatibility Complex (MHC) ligands for which 3D structures of complexes with antibodies, T-cell receptors or MHC molecules are available in the Protein Data Bank (PDB). Journal articles that are primary citations of PDB structures and that define immune epitopes are curated within IEDB along with accompanying functional assays and immunologically relevant information. For each curated structure, IEDB-3D provides calculated data on intermolecular contacts and interface areas and includes an application, EpitopeViewer, to visualize the structures. IEDB-3D is fully embedded within IEDB, thus allowing structural data, both curated and calculated, and all accompanying information to be queried using multiple search interfaces. These include queries for epitopes recognized in different pathogens, eliciting different functional immune responses, and recognized by different components of the immune system.

NAR Database Issue 2011
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tagsantibodies antigen receptors b-lymphocyte epitopes epitopes histocompatibility antigens ligands protein conformation protein databases t-lymphocyte epitopes

SVMHCTool Content

http://www-abi.informatik.uni-tuebingen.de/Services/SVMHC/

DNA > Sequence Polymorphisms
Human Genome > Other Resources
Human Genome > Sequence Polymorphisms
Protein > Interactions, Pathways, Enzymes

SVMHC is a server for prediction of MHC class I and class II binding peptides. SVMHC can be used to find likely binders in a protein sequence and to investigate the effects of single nucleotide polymorphisms on MHC-peptide binding.

NAR Web Server Issue 2006
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tagsalleles animals artificial intelligence computational biology histocompatibility antigens histocompatibility antigens class i hla antigens humans mice peptides predictive value of tests protein binding protein databases protein sequence analysis sensitivity and specificity single nucleotide polymorphism t-lymphocyte epitopes