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Links tagged with 'gene targeting'

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IKMCDatabase Content

http://www.knockoutmouse.org

Model Organisms > Databases

The International Knockout Mouse Consortium (IKMC) database and web portal serves as the central public web site for IKMC data. Researchers can access up-to-date information on IKMC knockout vectors, ES cells and mice for specific genes, and follow links to the respective repositories from which corresponding IKMC products can be ordered. Researchers can also use the web site to nominate genes for targeting, or to indicate that targeting of a gene should receive high priority. The IKMC database provides data to, and features extensive interconnections with, other community databases.

NAR Database Issue 2011
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tagsalleles animals biomedical research database management systems embryonic stem cells gene knockout techniques gene targeting genetic databases genetic vectors genomics humans international cooperation knockout mice mice molecular sequence annotation phenotype societies

MYBSTool Content

http://cg1.iis.sinica.edu.tw/~mybs/index.php

DNA > Structure and Sequence Feature Detection
Expression > Gene Regulation
Model Organisms > Yeast

MYBS (Mining Yeast Binding Sites) is a tool for mapping Transcription factors (TFs) and their binding sites (TFBSs) that integrates both experimentally verified (ChIP-chip data) and predicted position weight matrixes (PWMs) from several databases.

NAR Web Server Issue 2007
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tagsalgorithms base sequence binding sites computational biology dna sequence analysis gene targeting molecular sequence data oligonucleotide array sequence analysis protein binding saccharomyces cerevisiae saccharomyces cerevisiae proteins sequence alignment transcription factors

Zinc Finger ToolsTool Content

http://www.scripps.edu/mb/barbas/zfdesign/zfdesignhome.php

DNA > Structure and Sequence Feature Detection
Expression > Gene Regulation

Zinc Finger Tools provides several tools for selecting zinc finger protein target sites and for designing the proteins that will target them.

NAR Web Server Issue 2006
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tagsamino acid sequence animals base sequence binding sites biomolecular nuclear magnetic resonance cell line combinatorial chemistry techniques computer simulation deoxyribonuclease i deoxyribonucleases dna dna primers dna sequence analysis dna-binding proteins down-regulation drug design enzyme-linked immunosorbent assay epidermal growth factor receptor erbb genes erbb-1 genes erbb-2 genes erbb-2 receptor erbb-3 receptor flow cytometry gene expression profiling gene expression regulation gene library gene targeting genetic promoter regions genetic transcription green fluorescent proteins histidine human genome humans kidney luminescent proteins lysine mice molecular cloning molecular models molecular sequence data mutation nucleic acid conformation oligonucleotides peptide library pliability polymerase chain reaction protein conformation protein engineering proteomics recombinant proteins reporter genes retroviridae secondary protein structure sequence analysis site-directed mutagenesis substrate specificity tertiary protein structure transcription factors transfection up-regulation x-ray crystallography zinc fingers